| Alternative title | ALNP-1 : Matériau de référence certifié de nanoparticules de lipidiques anioniques |
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| DOI | Resolve DOI: https://doi.org/10.4224/crm.2023.alnp-1 |
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| Author | Search for: Jakubek, Zygmunt1ORCID identifier: https://orcid.org/0000-0003-3307-8464; Search for: Chen, Sam2; Search for: Tam, Yuen Yi C.2; Search for: Zou, Shan1ORCID identifier: https://orcid.org/0000-0002-2480-6821 |
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| Affiliation | - National Research Council of Canada
- Integrated Nanotherapeutics, Burnaby, BC, V5G 4X4, Canada
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| Format | 3D, Material |
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| Material type | Calibration solution |
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| Subject | Canadian reference material; nanoparticles |
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| Abstract | The ALNP-1 certified reference material (CRM) is a stable and homogeneous dispersion of anionic lipid nanoparticles of known provenance intended for methods development, inter-laboratory comparisons, verification of instrument performance, quality control, and general laboratory use to increase the confidence of size measurements of lipid-based as well as other soft nanoparticle formulations by dynamic light scattering. A single ALNP-1 vial contains minimum 2 mg of anionic lipid nanoparticles dispersed in 1 mL of 0.5x Dulbecco phosphate buffered saline (PBS) 15% sucrose. |
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| Publication date | 2023-03-01 |
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| Publisher | National Research Council of Canada |
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| Copyright statement | - © 2023
National Research Council of Canada
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| Access condition | |
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| References | View items (5)- Guide to the expression of uncertainty in measurement (GUM) (1 September 2008). https://www.bipm.org/en/publications/guides.
- International Standard ISO 22412:2017. Particle size analysis — Dynamic light scattering (DLS) (1 February 2017). https://www.iso.org/standard/65410.html.
- International Standard ISO/TR 3666:1998. Viscosity of Water (1 December 1998). https://www.iso.org/standard/28607.html.
- Liu, Yan-Sheng, Yu-Feng Hu, Qing-Cheng Hao, Xian-Ming Zhang, Zhi-Chang Liu, and Ji-Guang Li. ‘Viscosity and Density of the System NaCl + LaCl3 + H2O and Its Binary Subsystems at Different Temperatures’. Journal of Chemical & Engineering Data 54, no. 3 (5 January 2009): 739–44. https://doi.org/10.1021/je8004062.
- Viscosities of Sucrose Solutions at Various Temperatures: Tables of Recalculated Values (31 July 1958). https://nvlpubs.nist.gov/nistpubs/Legacy/circ/nbscircular440sup.pdf.
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| Export citation | Export as RIS |
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| Collection | Canadian Reference Materials and Methods |
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| Record identifier | 87a08e42-81b5-475c-bce1-d396ebf2dd3e |
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| Record created | 2023-04-26 |
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| Record modified | 2025-04-16 |
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