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MCLA: Certified Calibration Solution for Microcystin-LA

From National Research Council Canada

Alternative titleMCLA : Solution d’étalonnage certifiée de la microcystine-LA
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DOIResolve DOI: https://doi.org/10.4224/crm.2022.mcla.20210128
AuthorSearch for: 1ORCID identifier: https://orcid.org/0000-0002-4850-5863; Search for: 1; Search for: 1; Search for: 1; Search for: 1ORCID identifier: https://orcid.org/0000-0001-8537-4439; Search for: 1ORCID identifier: https://orcid.org/0000-0002-7746-8432
Affiliation
  1. National Research Council Canada
Format3D, Material
Material typeCalibration solution
SubjectCanadian reference material; microcystins; microcystin-LA
Abstract
CRM-MCLA is a certified calibration solution designed for analytical method development and accurate quantitation of MC-LA. The concentration is suitable for preparing a dilution series for calibration of instruments such as liquid chromatography with detection by ultraviolet absorbance (LC–UV) or mass spectrometry (LC–MS), as well as for spiking control samples for recovery experiments.
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PublisherNational Research Council Canada
Copyright statement
  • © 2022 National Research Council Canada
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References
View items (7)
  1. Carmichael, Wayne W. ‘The Toxins of Cyanobacteria’. Scientific American 270, no. 1 (January 1994): 78–86. .
  2. Pick, Frances R. ‘Blooming Algae: A Canadian Perspective on the Rise of Toxic Cyanobacteria’. Canadian Journal of Fisheries and Aquatic Sciences 73, no. 7 (July 2016): 1149–58. .
  3. Thomas, Krista, Dominik Wechsler, Yi-Min Chen, Sheila Crain, and Michael A Quilliam. ‘Analysis of Natural Toxins by Liquid Chromatography-Chemiluminescence Nitrogen Detection and Application to the Preparation of Certified Reference Materials’. Journal of AOAC INTERNATIONAL 99, no. 5 (1 September 2016): 1173–84. .
  4. Burton, Ian W., Michael A. Quilliam, and John A. Walter. ‘Quantitative 1H NMR with External Standards: Use in Preparation of Calibration Solutions for Algal Toxins and Other Natural Products’. Analytical Chemistry 77, no. 10 (26 March 2005): 3123–31. .
  5. Pauwels, J., A. van der Veen, A. Lamberty, and H. Schimmel. ‘Evaluation of Uncertainty of Reference Materials’. Accreditation and Quality Assurance 5, no. 3 (3 March 2000): 95–99. .
  6. Evaluation of measurement data – Supplement 1 to the “Guide to the expression of uncertainty in measurement” (GUM) – Propagation of distributions using a Monte Carlo method (1 January 2008). .
  7. Arman, Tarana, and John Clarke. ‘Microcystin Toxicokinetics, Molecular Toxicology, and Pathophysiology in Preclinical Rodent Models and Humans’. Toxins 13, no. 8 (29 July 2021): 537. .
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CollectionCanadian Reference Materials and Methods
Record identifier58dfa29d-e68e-4df2-8566-462d8ef46a39
Record created2022-07-19
Record modified2025-11-20
Date modified: